Search results for "Mitral Valve Replacement"

showing 10 items of 17 documents

Endocarditis due to Abiotrophia defectiva, a biofilm-related infection associated with the presence of fixed braces

2017

Abstract Rationale: Endocarditis with Abiotrophia defectiva represents 4.3% to 6% of all streptococcal endocarditis. The article presents diagnosis issues and the complexity of the treatment. Patient concerns: We present the case of a female white patient, aged 26 years, who developed infectious endocarditis caused by A defectiva, in the last trimester of pregnancy, a biofilm-related infection associated with the presence of fixed braces. Diagnoses: The diagnosis of infectious endocarditis was confirmed by the cardiac ultrasound examination that revealed a voluminous vegetation on the mitral valve, and acute mitral regurgitation caused by chordae tendinae rupture, and also by isolating Abio…

Adult0301 basic medicinemedicine.medical_specialtyProsthesis-Related Infectionsmedicine.drug_classmedicine.medical_treatment030106 microbiologyAntibioticsbiofilm03 medical and health sciences0302 clinical medicinePregnancyAbiotrophiaMitral valvemedicineHumansEndocarditisClinical Case Report030212 general & internal medicinePregnancy Complications InfectiousAbiotrophia defectivaGram-Positive Bacterial InfectionsAbiotrophia defectivaBracesinfectious endocarditisbiology4900business.industryMitral valve replacementEndocarditis BacterialGeneral MedicineAbiotrophiabiology.organism_classificationmedicine.diseaseSurgerymedicine.anatomical_structureEmbolismBiofilmsInfective endocarditisFemalebusinessResearch ArticleMedicine
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Numerical simulation of transcatheter mitral valve replacement: The dynamic implication of LVOT obstruction in the valve-in-ring case.

2022

Transcatheter mitral valve replacement (TMVR) has been used for “off-label” treatment when annuloplasty band ring for mitral repair fails. However, the complex anatomy and function of the mitral valve may lead to fatal complications as a result of the left ventricular outflow tract (LVOT) obstruction in TMVR. We report the structural and hemodynamic response of LVOT obstruction resulting from TMVR with the Edwards SAPIEN 3 Ultra (S3) device. We modified the original Living Heart Human Model (LHHM) to account for a failed mitral valve with an annuloplasty band ring and simulated the cardiac beating condition in the setting of S3 device implantation. Findings demonstrated a high dynamic behav…

Heart Valve Prosthesis ImplantationHeart Defects CongenitalHistoryCardiac CatheterizationPolymers and PlasticsRehabilitationBiomedical EngineeringBiophysicsMitral Valve InsufficiencyFinite Element (FE) analysisIndustrial and Manufacturing EngineeringVentricular Outflow ObstructionTreatment OutcomeRisk FactorsComputational Fluid Dynamic (CFD)Living heart human modelHeart Valve ProsthesisHumansMitral ValveOrthopedics and Sports MedicineBusiness and International ManagementTranscatheter mitral valve replacementJournal of biomechanics
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Impact of Prosthesis-Patient Mismatch after Mitral Valve Replacement

2016

Background and aim of the study: The study aim was to determine the impact of prosthesis-patient mismatch (PPM) on early and late clinical outcomes, left atrial and ventricular remodeling, late tricuspid valve regurgitation and pulmonary hypertension (PH) in patients after mitral valve replacement (MVR). Methods: A total of 46 patients (mean age 66 ± 9.3 years) with mitral valve diseases and undergoing isolated MVR was enrolled in the study. The mitral valve effective orifice area (EOA) was determined using the continuity equation and indexed for the patient’s body surface area (EOAi). PPM was defined as EOAi ≤1.2 cm2/m2. PH was defined as a systolic pulmonary artery pressure (sPAP) >40 mmH…

Heart Valve Prosthesis ImplantationMaleProsthesis-Patient MismatchHypertension PulmonaryHemodynamicsMitral Valve InsufficiencySettore MED/23 - Chirurgia CardiacaMitral Valve ReplacementMiddle AgedTricuspid Valve InsufficiencyTreatment OutcomeRisk FactorsHeart Valve ProsthesisProsthesis FittingHumansSettore MED/05 - Patologia ClinicaFemaleEmergenciesHospitals TeachingProsthesis-Patient Mismatch; Mitral Valve ReplacementAgedRetrospective Studies
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Preoperative evaluation before MitraClip®: present and future perspective.

2014

ABSTRACT  Mitral regurgitation (MR) is the second most common heart valve disease worldwide. Currently, the management of MR is based on medical therapy (including biventricular pacing), surgery (mitral valve replacement or repair) and percutaneous therapy. However, in spite of guideline recommendations, 50% of individuals assessed in the Euro Heart Survey were not referred to surgical intervention due to comorbidities or real or perceived high risks for cardiac surgery; thus, in recent years, the focus of research has shifted to the development of percutaneous approaches to treat severe MR in order to restore valve function in a minimally invasive fashion. Among these techniques, the perc…

Heart Valve Prosthesis ImplantationMitral regurgitationmedicine.medical_specialtyPercutaneousbusiness.industrymedicine.medical_treatmentMitraClipPatient SelectionMitral valve replacementMitral Valve InsufficiencyGuidelineSurgeryCardiac surgerymedicine.anatomical_structureHeart Valve ProsthesisPreoperative CaremedicineMolecular MedicineHumansMitral ValveHeart valveCardiology and Cardiovascular MedicinebusinessPercutaneous Mitral Valve Repair
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Cross-clamping a porcelain aorta: an alternative technique for high-risk patients

2018

Background Aortic cross-clamping in patients with porcelain aorta is associated with high mortality and morbidity rates. The aim is to establish a new approach to improve the outcome in this high-risk population. Methods Between September 2007 and November 2012, 42 patients with an aortic (N.=33; 81.3±6.4 years) or mitral valve disease (N.=9; 80.3±5.7) combined with a porcelain aorta underwent aortic (AVR) or mitral valve replacement (MVR). After arterial cannulation via distal aortic arch or femoral artery, longitudinal aortotomy under total cardiopulmonary bypass (CPB) was performed. The aorta was slowly clamped, thus mobilized atherosclerotic material could leave the aorta through the op…

MaleAortic archmedicine.medical_specialtyTime Factorsmedicine.medical_treatmentOperative TimePopulationAortic DiseasesHeart Valve Diseases030204 cardiovascular system & hematologylaw.invention03 medical and health sciencesPostoperative Complications0302 clinical medicineRisk Factorslawmedicine.arteryInternal medicineMitral valveAscending aortaCardiopulmonary bypassHumansMedicineVascular CalcificationeducationStrokeAgedRetrospective StudiesAged 80 and overHeart Valve Prosthesis Implantationeducation.field_of_studyAortaCardiopulmonary Bypassbusiness.industryMitral valve replacementGeneral Medicinemedicine.diseaseConstrictionTreatment Outcomemedicine.anatomical_structure030228 respiratory systemAortic Valvecardiovascular systemCardiologyMitral ValveFemaleSurgeryCardiology and Cardiovascular MedicinebusinessThe Journal of Cardiovascular Surgery
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Inhaled Prostacyclin, Nitric Oxide, and Nitroprusside in Pulmonary Hypertension After Mitral Valve Replacement

2005

Abstract Objective: Pulmonary hypertension increases morbidity and mortality in patients undergoing heart surgery. Mitral valve stenosis is frequently associated with an increase in pulmonary vascular resistance (PVR). Cardiopulmonary bypass exacerbates pulmonary hypertension in patients undergoing cardiac surgery. The aim of this study was to compare the hemodynamic effects of inhaled prostacyclin and nitric oxide and the administration of i.v. nitroprusside during cardiac surgery with a clinical, pharmacodynamic dose-response, prospective, randomized, and double-blind study (Group A: inhaled prostacyclin; Group B: inhaled nitric oxide; Group C: nitroprusside). Materials and Methods: Fifty…

MaleNitroprussidePulmonary and Respiratory Medicinemedicine.medical_specialtyCardiac outputHypertension Pulmonarymedicine.medical_treatmentProstacyclinNitric OxideNitric oxidechemistry.chemical_compoundMitral valve stenosisDouble-Blind MethodInternal medicineAdministration InhalationmedicineHumansMitral Valve StenosisAntihypertensive AgentsEndothelium-Dependent Relaxing FactorsHeart Valve Prosthesis ImplantationCardiopulmonary Bypassbusiness.industryMitral valve replacementMiddle Agedmedicine.diseaseEpoprostenolPulmonary hypertensionCardiac surgerymedicine.anatomical_structurechemistryAnesthesiacardiovascular systemCardiologyVascular resistanceMitral ValveFemaleSurgeryCardiology and Cardiovascular Medicinebusinessmedicine.drugJournal of Cardiac Surgery
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Is the Serum N Terminal Pro-Brain Natriuretic Peptide the Best Candidate Biomarker for Long-term Prognosis in Patients with Prosthesis-patient Mismat…

2014

AGE8. Is the Serum N Terminal Pro-Brain Natriuretic Peptide the Best Candidate Biomarker for Long-term Prognosis in Patients with Prosthesis-patient Mismatch after Mitral Valve Replacement? C. R. Balistreri1, C. Pisano1, R. Franchino1, S.R. Vacirca1, F. Crapanzano1, O. F. Triolo1, C. Palmeri1, G. Ruvolo1 1University Of Palermo, Palermo, Italy Background: Natriuretic peptides (NPs) are released from the heart in response to pressure and volume overload. Among these, B-NP and Nterminal- proBNP (NT-proBNP) have become important diagnostic tools for the management of heart failure. However, B-NP and NT-proBNP levels reflect complications of systolic and diastolic function as well as alteration …

Natriuretic peptides (NPs) B-NP and Nterminal- proBNP (NT-proBNP) prosthesis patient mismatch (PPM) mitral valve replacement (MVR)
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Outcome after mitral valve operations with depressed left ventricular function.

2012

We retrospectively investigated 42 patients (27 men, 15 women; mean age, 67 years) with severe mitral valve incompetence and endstage cardiomyopathy (ejection fraction <30%) who were operated on between January 2002 and March 2009. Of these, 14 were in New York Heart Association class IV, and 27 were in class III. The etiology was ischemic in 18 patients and idiopathic dilated in 24. Mitral valve repair was performed in 25 patients, and 17 had mitral valve replacement. The mean logistic EuroSCORE was 33.41. The mean follow-up was 44.52 months. There were no perioperative deaths. Three patients died within 30 days postoperatively. Thirty-day mortality was lower than predicted by EuroSCOR…

Pulmonary and Respiratory MedicineAdultMaleReoperationmedicine.medical_specialtyTime Factorsmedicine.medical_treatmentCardiomyopathyKaplan-Meier EstimateRisk AssessmentSeverity of Illness IndexVentricular Function LeftVentricular Dysfunction LeftRisk FactorsInternal medicineMitral valveGermanymedicineHumansCardiac Surgical ProceduresSurvival rateAgedProportional Hazards ModelsRetrospective StudiesAged 80 and overHeart Valve Prosthesis ImplantationMitral valve repairEjection fractionbusiness.industryMitral valve replacementMitral Valve InsufficiencyEuroSCOREStroke VolumeGeneral MedicinePerioperativeMiddle Agedmedicine.diseaseSurgerymedicine.anatomical_structureLogistic ModelsTreatment OutcomeMultivariate AnalysisCardiologyMitral ValveSurgeryFemaleCardiology and Cardiovascular MedicinebusinessCardiomyopathiesAsian cardiovascularthoracic annals
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Diagnosis of papillary muscle rupture after acute myocardial infarction by transthoracic and transesophageal echocardiography.

1993

The sensitivity of transthoracic echocardiography to visualize the structural abnormality of papillary muscle rupture (PMR) after acute myocardial infarction can be anticipated to average about 50%; therefore, we evaluated five patients exhibiting the condition with both transthoracic and transesophageal echocardiography. The use of the two imaging techniques resulted in the fact that no instance of PMR was missed. Using transthoracic echocardiography in two patients and transesophageal echocardiography in four, the ruptured papillary muscle was visualized directly. Mitral insufficiency as an indirect sign was observed in all patients. In one patient the papillary muscle rupture developed i…

ThoraxMalemedicine.medical_specialtymedicine.medical_treatmentMitral valveInternal medicineMedicineEndocarditisHumansMyocardial infarctionEsophagusPapillary muscleAgedHeart Rupture Post-Infarctionbusiness.industryMitral valve replacementGeneral MedicineMiddle AgedPapillary Musclesmedicine.diseasemedicine.anatomical_structureEchocardiographyEvaluation Studies as TopicCardiologyFemaleRadiologyCardiology and Cardiovascular MedicinebusinessEchocardiography TransesophagealArteryClinical cardiology
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On the Modeling of Transcatheter Therapies for the Aortic and Mitral Valves: A Review

2022

Transcatheter aortic valve replacement (TAVR) has become a milestone for the management of aortic stenosis in a growing number of patients who are unfavorable candidates for surgery. With the new generation of transcatheter heart valves (THV), the feasibility of transcatheter mitral valve replacement (TMVR) for degenerated mitral bioprostheses and failed annuloplasty rings has been demonstrated. In this setting, computational simulations are modernizing the preoperative planning of transcatheter heart valve interventions by predicting the outcome of the bioprosthesis interaction with the human host in a patient-specific fashion. However, computational modeling needs to carry out increasingl…

in silico modeltranscatheter mitral valve replacementtranscatheter aortic valve replacementcomputational fluid dynamicsGeneral MedicineProsthesis
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